Treatment failure due to extended spectrum βlactamase

Antimicrobial Treatment of Experimental Infection Due to an Extended-spectrum ß- Lactamase-producing Klebsiella Pneumoniae Strain

Fulminant hepatic failure due to metastatic choroidal melanoma

Epinephrine in the treatment of cardiac failure due to shunts.

Treatment failure of tuberculosis due to concomitant pathology.

Introduction Tuberculosis is a worldwide problem. Nearly 3 million cases of tuberculosis occur per year in Southeast Asia alone.1 Several factors contribute to treatment failure and significant morbidity and mortality. While the most common causes in the "Third World" include poor compliance, late presentation, improper therapy, and the development of drug resistance2, underdiagnosis of this di...

Empiric Piperacillin-Tazobactam versus Carbapenems in the Treatment of Bacteraemia Due to Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae are a common cause of bacteraemia in endemic countries and may be associated with high mortality; carbapenems are considered the drug of choice. Limited data suggest piperacillin-tazobactam could be equally effective. We aimed to compare 30-day mortality of patients treated empirically with piperacillin-tazobactam versus a car...